hrp0086p1-p907 | Thyroid P1 | ESPE2016

Dysregulation of the Immune System in Children with Graves Disease – the Role of NK and NKT-Like Cells

Klatka Maria , Polak Agnieszka , Grywalska Ewelina , Kollataj Witold , Rolinski Jacek

Background: Almost all cases of hyperthyroidism in children result from GravesÂ’ disease (GD). Recent studies have confirmed a significant role of T cells in the development of autoimmune diseases. However, the interactions between NKT-like cells and NK cells in GD are still poorly understood.Objective and hypotheses: The aim of the study was to assess the frequencies of peripheral blood T, NK and NKT-like cells in children with GD.<p class="abst...